Definition
It works in a negative feedback loop. When blood glucose levels change a hormone is secreted to oppose the change. The action of the hormone cannot occur continually as at a certain point the other hormone is released resulting in the other effect. This continues on a loop of the 2 hormones being produced.
- If glucose levels are too high:
- The pancreas secretes insulin.
- Insulin binds to cells in the target organs causing:
- Glucose to move from blood to muscles for respiration
- Excess glucose to be converted to glycogen.
- If glucose levels are too low:
- The pancreas secrets glucagon
- Glucagon binds to the livers cells causing glycogen to be broken down into glucose which is released into the blood.
Diabetes
Type 1
The pancreas can not produce enough insulin so blood glucose levels can rise to fatal amounts Is treated with insulin injections at meal times.
Type 2
Cells no longer respond to insulin Treated by certain drugs and diet change Obesity is a risk factor.